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I know you all are going to say there is no such thing as a safe prohormone,but which has the least side effects and is most effective?Reps 08-05-2008, 05:50 PM #2Some of the best and safest prohormones include: #1: Epistane (EPI) Epistane of EPI is a DHT derived prohormone that can add lean muscle while also cutting fat. Non-methylated prohormones are safer to stack since they put less strain on the liver. The best natural alternatives to prohormone for building muscle are GDA's, HMB, BCAA's, EAA's, Phosphatidic Acid and natural test boosters. When it comes to prohormones, while there's a lot of different ingredients and compounds, two of the most popular, most common, and most asked about are 1-Andro and 4-Andro prohormones. Therefore, it is much more logical to use either steroids, which will have the same side effects at. M1,4ADD is the prohormone to the anabolic Dianabol, loved by bodybuilders for the mass and strength gains it brings. androgen-anabolic steroid - it has an enormously strong anti-estrogenic effect. Prohormones generally wreck your cholesterol/hdl/ldl ratios and im not sure of your other health markers but your lifetime cardiovascular risk is going to be >50% as it stands now. You have to run compounds that will increase muscle mass or at least stop muscle loss when cutting, but you would want to avoid the worst side effects. The best prohormone will depend on your goals and experience but PH's should only be used by males 21+ with a clear understanding of cycle support and PCT supplements. Although it is a safe prohormone to supplement with, one can never be too sure! It is recommended to intake 100 mg to 200 mg of the drug. 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